Clinical Question/Best Level of Evidence - Internal Medicine Bedside EBM Program

Type of Clinical Question	Suggested Level of Evidence
Therapy	RCT > cohort > case control > case series
Diagnosis	Prospective, blind comparison to a gold standard
Etiology/Harm	RCT > cohort > case control > case series
Prognosis	Cohort study > case control > case series
Prevention	RCT > cohort study > case control > case series
Clinical Exam	Prospective, blind comparison to gold standard
Cost	economic analysis

Questions of therapy, etiology, and prevention, which can best be answered by a RCT, can also be answered by a meta-analysis or systematic review.

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Type of Clinical Question