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Newark  New Brunswick/Piscataway
Stratford Camden
<span class="subhead">South
Jersey Medical</span> History </div></TD>
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<span class="big">Lewis L. Coriell<br>
</span><span class="subhead">1911-2001</span>
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<p><span class="subhead">The Coriell Institute for Medical
Research</span> </p>
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<p><a href="http://www.coriell.org/about/coriellll.html">Dr. Coriell</a> served
in the army from 1943 through 1946. There he met R.F. McNair Scott, Director
of Research at Children's Hospital, who arranged for Coriell to finish his residency
in pediatrics at Children's Hospital of Philadelphia. While at CHOP, Coriell
ran Tom Scott's research laboratory on herpes simplex virus and growing chicken
pox virus in human tissue. John F. Enders of Harvard visited the lab and later
tried the procedure on polio virus. He, Frederick Robbins, and Thomas
Waller later received a Nobel Prize for growing the polio virus! </p>
<p>In 1948, <a href="http://www4.umdnj.edu/camlbweb/sjmedhist/reuben.html">Reuben
Sharp</a> and Thack Read, president and secretary respectively of the Camden
County Medical Society, were looking for a director for the Camden Municipal
Hospital for Contagious Diseases. Dr. Coriell was made director
of the hospital, where residents from Children's Hospital, the Children's Hospital,
Penn's Department of Medicine, and the Naval Hospital were exposed to treating
contagious diseases. Penn and the Camden County Medical Society each agreed
to provide a consultant in every specialty to be on call. Medical students
came once a week for rounds.
<p>Patients at the Camden Municipal
Hospital were treated for a wide variety of contagious diseases:
<center><table BORDER=0 CELLSPACING=10 COLS=2 WIDTH="85%" >
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<td VALIGN=TOP>Diphtheria
<br>Tetanus
<br>Whooping cough
<br>Meningitis
<br>Typhoid fever
<br>Polio
<br>Osteomyelitis</td>
<td VALIGN=TOP>Encephalitis
<br>Rocky Mountain spotted fever
<br>Anthrax (from hide factories in
the area)
<br>Scarlet fever
<br>Rheumatic fever
<br>Complications from measles, mumps,
and chicken pox</td>
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In 1951 Bill Hammon, Professor of Epidemiology
at Pittsburgh, and Joe Stokes, of Children's Hospital, received a grant
from the March of Dimes to try gamma globulin to prevent polio. They asked
Dr. Coriell to run field trials, double blind studies in communities undergoing
an epidemic. The study was conducted in Provo, UT in 1951, Houston in 1952,
and Sioux City, IA in 1952.
<p>Following the success of the field
trials and an article in the November 2, 1952 Saturday Evening Post, the
community asked what they could do for Dr. Coriell. Since his patients
were in Camden, his laboratory was at Children's Hospital in Philadelphia,
and the lab monkeys were housed at Garden State Race Track, he asked for
a research laboratory.
<p>In 1953, Jonas Salk began field trials
of his vaccine, funded by the March of Dimes, in about 20 states. About
¼ to 1/3 of the blood samples were sent to the Camden Municipal
Hospital, where Dr. Coriell's team was proficient in running the tests.
Five companies agreed to produce the vaccine. Dr. Coriell and his colleague
Dr. McAllister helped Wyeth, get started. They turned out to be the first
company to receive FDA approval.
<p>The South Jersey Medical Research
Foundation was chartered by the State of New Jersey on November 3, 1953
and dedicated in June 1956. The name was later changed to the Institute
for Medical Research. Developments that came from Dr. Coriell's Institute
include:
<ul>
<li>
Cell culture techniques</li>
<li>
HEPA filtered hoods for working in a
sterile atmosphere</li>
<li>
Biohazard hoods, later adopted for hip
surgery</li>
</ul>
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<span class="subhead">Read more about Dr. Coriell: </span>
<p><a href="http://www.coriell.org/about/coriellll.html">In Memoriam: Lewis L.
Coriell Md PhD, 1911 - 2001</a><br>
<a href="http://www4.umdnj.edu/camlbweb/sjmedhist/frozenforlife1.html">Frozen
for Life</a><i> (Mapping New Territory in... New Jersey: The State of Research</i>.
Union, NJ: <a href="http://www.njabr.org/">New Jersey Association for Biomedical
Research</a>, 2001.)
<p>Return to <a href="http://www4.umdnj.edu/camlbweb/sjmedhist/">South
Jersey Medical History</a>. </td>
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