JAMA 267(11):1484-1488, 1992.

Lymphocyte subsets in healthy children during the first 5 years of life.

Denney T, Yogev R, Gelman R, Skuza C, Oleske J, Chadwick E, Cheng SC, Connor E.

The following data was collected from specimens prepared using the whole blood lysis method. Data are 5th and 95th percentile ranges (confidence interval). Data distribution was normalized when necessary by mathematical transformation (ie: log, square root, etc.). (Note: 92% of these children were Hispanic.)

Pediatric Peripheral Blood

95% Confidence Interval
Percentage Cells per cu.mm
CD Age N Min Max Min Max
CD3 2-3 mo 52 60 87 2,070 6,540
4-8 mo 95 57 84 2,280 6,450
12-23 mo 39 53 81 1,460 5,440
24-59 mo 22 62 80 1,610 4,230
CD4 2-3 mo 52 41 64 1,460 5,110
4-8 mo 95 36 61 1,690 4,600
12-23 mo 39 31 54 1,020 3,600
24-59 mo 22 35 51 900 2,860
CD8 2-3 mo 52 16 35 650 6,540
4-8 mo 95 16 34 720 6,450
12-23 mo 39 16 38 570 5,440
24-59 mo 22 22 38 630 4,230